Prospective analysis of body mass index, physical activity and colorectal cancer risk associated with β-catenin (CTNNB1) status

Dysregulation of the WNT/β-catenin (CTNNB1) signaling pathway is implicated in colorectal carcinoma and metabolic diseases. Considering these roles and cancer prevention, we hypothesized that tumor CTNNB1 status might influence cellular sensitivity to obesity and physical activity. In clinical follo...

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Autori principali: Morikawa, Teppei, Kuchiba, Aya, Lochhead, Paul, Nishihara, Reiko, Yamauchi, Mai, Imamura, Yu, Liao, Xiaoyun, Qian, Zhi Rong, Ng, Kimmie, Chan, Andrew T., Meyerhardt, Jeffrey A., Giovannucci, Edward, Fuchs, Charles S., Ogino, Shuji
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594537/
https://ncbi.nlm.nih.gov/pubmed/23442321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2276
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