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Retinoic Acid Hypersensitivity Promotes Peripheral Tolerance in Recent Thymic Emigrants

Whereas thymic education eliminates most self-reactive T cells, additional mechanisms to promote tolerance in the periphery are critical to prevent excessive immune responses against benign environmental antigens and some self-antigens. Here we show that murine CD4(+) recent thymic emigrants (RTEs)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bhaumik, Suniti, Giffon, Thierry, Bolinger, Derek, Kirkman, Richard, Lewis, David B., Weaver, Casey T., Randolph, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594456/
https://ncbi.nlm.nih.gov/pubmed/23401586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200852
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