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Retinoic Acid Hypersensitivity Promotes Peripheral Tolerance in Recent Thymic Emigrants

Whereas thymic education eliminates most self-reactive T cells, additional mechanisms to promote tolerance in the periphery are critical to prevent excessive immune responses against benign environmental antigens and some self-antigens. Here we show that murine CD4(+) recent thymic emigrants (RTEs)...

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Detalhes bibliográficos
Main Authors: Bhaumik, Suniti, Giffon, Thierry, Bolinger, Derek, Kirkman, Richard, Lewis, David B., Weaver, Casey T., Randolph, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594456/
https://ncbi.nlm.nih.gov/pubmed/23401586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200852
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