Human CD4(+) T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function

CD4(+) recent thymic emigrants (RTEs) comprise a clinically and immunologically important T cell population that indicates thymic output and that is essential for maintaining a diverse αβ–T cell receptor (TCR) repertoire of the naive CD4(+) T cell compartment. However, their frequency and function a...

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Autores principales: Haines, Christopher J., Giffon, Thierry D., Lu, Li-Sheng, Lu, Xiaowei, Tessier-Lavigne, Marc, Ross, Douglas T., Lewis, David B.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2009
Materias:
Brief Definitive Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646563/
https://ncbi.nlm.nih.gov/pubmed/19171767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080996
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