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Dysregulation of brain adenosine is detrimental to the expression of conditioned freezing but not general Pavlovian learning

Glutamatergic and dopaminergic neurotransmission is modulated by adenosine, whose ambient level in the brain is in turn regulated by the metabolic enzyme, adenosine kinase (ADK). Brain adenosinergic tone can therefore be effectively reduced and increased by up- and down-regulation of ADK expression,...

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Bibliografiske detaljer
Main Authors: Singer, Philipp, Zhang, Chu-Chu, Boison, Detlev, Yee, Benjamin K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594379/
https://ncbi.nlm.nih.gov/pubmed/23290937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2012.12.012
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