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Dysregulation of brain adenosine is detrimental to the expression of conditioned freezing but not general Pavlovian learning
Glutamatergic and dopaminergic neurotransmission is modulated by adenosine, whose ambient level in the brain is in turn regulated by the metabolic enzyme, adenosine kinase (ADK). Brain adenosinergic tone can therefore be effectively reduced and increased by up- and down-regulation of ADK expression,...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594379/ https://ncbi.nlm.nih.gov/pubmed/23290937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2012.12.012 |
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