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Modulation of sensorimotor gating in prepulse inhibition by conditional brain glycine transporter 1 deletion in mice
Inhibition of glycine transporter 1 (GlyT1) augments N-methyl-D-aspartate receptor (NMDAR)-mediated transmission and represents a potential antipsychotic drug target according to the NMDAR hypofunction hypothesis of schizophrenia. Preclinical evaluation of GlyT1 inhibiting drugs using the prepulse i...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980791/ https://ncbi.nlm.nih.gov/pubmed/20647165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2010.06.014 |
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