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Modulation of sensorimotor gating in prepulse inhibition by conditional brain glycine transporter 1 deletion in mice

Inhibition of glycine transporter 1 (GlyT1) augments N-methyl-D-aspartate receptor (NMDAR)-mediated transmission and represents a potential antipsychotic drug target according to the NMDAR hypofunction hypothesis of schizophrenia. Preclinical evaluation of GlyT1 inhibiting drugs using the prepulse i...

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Bibliografski detalji
Glavni autori: Singer, Philipp, Boison, Detlev, Möhler, Hanns, Feldon, Joram, Yee, Benjamin K.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980791/
https://ncbi.nlm.nih.gov/pubmed/20647165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2010.06.014
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