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Altered mnemonic functions and resistance to NMDA receptor antagonism by forebrain conditional knockout of glycine transporter 1

Converging evidence from pharmacological and molecular studies has led to the suggestion that inhibition of glycine transporter 1 (GlyT1) constitutes an effective means to boost N-methyl-D-aspartate receptor (NMDAR) activity by increasing the extra-cellular concentration of glycine in the vicinity o...

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Detalhes bibliográficos
Main Authors: Singer, Philipp, Yee, Benjamin K., Feldon, Joram, Iwasato, Takuji, Itohara, Shigeyoshi, Grampp, Thomas, Prenosil, George, Benke, Dietmar, Möhler, Hanns, Boison, Detlev
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692764/
https://ncbi.nlm.nih.gov/pubmed/19332109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.03.056
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