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A general assay for monitoring the activities of protein tyrosine phosphatases in living eukaryotic cells
Protein tyrosine phosphatases (PTPs) are key signal-transduction regulators and have emerged as potential drug targets for inhibitor design. Here we report a yeast-based assay that provides a general means of assessing the activity and/or inhibition of essentially any classical PTP in living cells....
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594370/ https://ncbi.nlm.nih.gov/pubmed/23333221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.12.025 |
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