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Pharmacokinetics of Intravenous Voriconazole in Obese Patients: Implications of CYP2C19 Homozygous Poor Metabolizer Genotype

There is a paucity of pharmacokinetic studies describing weight-based dosing of intravenous (IV) voriconazole in obesity. We report the pharmacokinetics of IV voriconazole in an obese CYP2C19 homozygous poor metabolizer and review previously reported data of IV voriconazole in obesity. A 17-year-old...

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書誌詳細
主要な著者: Moriyama, Brad, Jarosinski, Paul F., Figg, William D., Henning, Stacey A., Danner, Robert L., Penzak, Scott R., Wayne, Alan S., Walsh, Thomas J.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594083/
https://ncbi.nlm.nih.gov/pubmed/23400848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1192
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