Pharmacokinetics of Intravenous Voriconazole in Obese Patients: Implications of CYP2C19 Homozygous Poor Metabolizer Genotype

There is a paucity of pharmacokinetic studies describing weight-based dosing of intravenous (IV) voriconazole in obesity. We report the pharmacokinetics of IV voriconazole in an obese CYP2C19 homozygous poor metabolizer and review previously reported data of IV voriconazole in obesity. A 17-year-old...

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Autors principals: Moriyama, Brad, Jarosinski, Paul F., Figg, William D., Henning, Stacey A., Danner, Robert L., Penzak, Scott R., Wayne, Alan S., Walsh, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594083/
https://ncbi.nlm.nih.gov/pubmed/23400848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1192
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