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Novel Bruton’s tyrosine kinase inhibitors currently in development
Bruton’s tyrosine kinase (Btk) is intimately involved in multiple signal-transduction pathways regulating survival, activation, proliferation, and differentiation of B-lineage lymphoid cells. Btk is overexpressed and constitutively active in several B-lineage lymphoid malignancies. Btk has emerged a...
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| Huvudupphovsmän: | , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Dove Medical Press
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594038/ https://ncbi.nlm.nih.gov/pubmed/23493945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S33732 |
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