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Novel Indications for Bruton’s Tyrosine Kinase Inhibitors, beyond Hematological Malignancies
Bruton’s tyrosine kinase (BTK) is a critical terminal enzyme in the B-cell antigen receptor (BCR) pathway. BTK activation has been implicated in the pathogenesis of certain B-cell malignancies. Targeting this pathway has emerged as a novel target in B-cell malignancies, of which ibrutinib is the fir...
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| Udgivet i: | J Clin Med |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5920436/ https://ncbi.nlm.nih.gov/pubmed/29561760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm7040062 |
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