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Regulatory Phosphorylation of Ikaros by Bruton's Tyrosine Kinase
Diminished Ikaros function has been implicated in the pathogenesis of acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. Therefore, a stringent regulation of Ikaros is of paramount importance for normal lymphocyte ontogeny. Here we provide genetic and biochemical evidence...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3747153/ https://ncbi.nlm.nih.gov/pubmed/23977012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071302 |
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