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Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros
Ikaros is a zinc finger-containing DNA-binding protein that plays a pivotal role in immune homeostasis through transcriptional regulation of the earliest stages of lymphocyte ontogeny and differentiation. Functional deficiency of Ikaros has been implicated in the pathogenesis of acute lymphoblastic...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497833/ https://ncbi.nlm.nih.gov/pubmed/23071339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209828109 |
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