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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
Glioblastoma (GB) is the most common and aggressive primary brain malignancy, with poor prognosis and a lack of effective therapeutic options. Accumulating evidence suggests that intratumor heterogeneity likely is the key to understanding treatment failure. However, the extent of intratumor heteroge...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593922/ https://ncbi.nlm.nih.gov/pubmed/23412337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219747110 |
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