Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics

Glioblastoma (GB) is the most common and aggressive primary brain malignancy, with poor prognosis and a lack of effective therapeutic options. Accumulating evidence suggests that intratumor heterogeneity likely is the key to understanding treatment failure. However, the extent of intratumor heteroge...

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Bibliografski detalji
Glavni autori: Sottoriva, Andrea, Spiteri, Inmaculada, Piccirillo, Sara G. M., Touloumis, Anestis, Collins, V. Peter, Marioni, John C., Curtis, Christina, Watts, Colin, Tavaré, Simon
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593922/
https://ncbi.nlm.nih.gov/pubmed/23412337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219747110
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