Ładuje się......
DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions
DNA damage leads to a halt in proliferation owing to apoptosis or senescence, which prevents transmission of DNA alterations. This cellular response depends on the tumor suppressor p53 and functions as a powerful barrier to tumor development. Adult stem cells are resistant to DNA damage-induced apop...
Zapisane w:
| Główni autorzy: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2013
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593901/ https://ncbi.nlm.nih.gov/pubmed/23417300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213394110 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|