Φορτώνει......
Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens
The S100A8/S100A9 heterodimer calprotectin (CP) functions in the host response to pathogens through a mechanism termed “nutritional immunity.” CP binds Mn(2+) and Zn(2+) with high affinity and starves bacteria of these essential nutrients. Combining biophysical, structural, and microbiological analy...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593839/ https://ncbi.nlm.nih.gov/pubmed/23431180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220341110 |
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