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Nutrient metal sequestration by calprotectin inhibits bacterial superoxide defense enhancing neutrophil killing of Staphylococcus aureus

By sequestering manganese and zinc, the neutrophil protein calprotectin plays a crucial role in host defense against bacterial and fungal pathogens. However, the essential processes disrupted by calprotectin remain unknown. We report that calprotectin enhances the sensitivity of Staphylococcus aureu...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Kehl-Fie, Thomas E., Chitayat, Seth, Hood, M. Indriati, Damo, Steven, Restrepo, Nicole, Garcia, Carlos, Munro, Kim A., Chazin, Walter J., Skaar, Eric P.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157011/
https://ncbi.nlm.nih.gov/pubmed/21843872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.07.004
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