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Nutrient metal sequestration by calprotectin inhibits bacterial superoxide defense enhancing neutrophil killing of Staphylococcus aureus

By sequestering manganese and zinc, the neutrophil protein calprotectin plays a crucial role in host defense against bacterial and fungal pathogens. However, the essential processes disrupted by calprotectin remain unknown. We report that calprotectin enhances the sensitivity of Staphylococcus aureu...

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Detalhes bibliográficos
Main Authors: Kehl-Fie, Thomas E., Chitayat, Seth, Hood, M. Indriati, Damo, Steven, Restrepo, Nicole, Garcia, Carlos, Munro, Kim A., Chazin, Walter J., Skaar, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157011/
https://ncbi.nlm.nih.gov/pubmed/21843872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.07.004
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