MntABC and MntH Contribute to Systemic Staphylococcus aureus Infection by Competing with Calprotectin for Nutrient Manganese

During infection, vertebrates limit access to manganese and zinc, starving invading pathogens, such as Staphylococcus aureus, of these essential metals in a process termed “nutritional immunity.” The manganese and zinc binding protein calprotectin is a key component of the nutrient-withholding respo...

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Hlavní autoři: Kehl-Fie, Thomas E., Zhang, Yaofang, Moore, Jessica L., Farrand, Allison J., Hood, M. Indriati, Rathi, Subodh, Chazin, Walter J., Caprioli, Richard M., Skaar, Eric P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754211/
https://ncbi.nlm.nih.gov/pubmed/23817615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00420-13
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