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Staphylococcus aureus lacking a functional MntABC manganese import system have increased resistance to copper.
S. aureus USA300 isolates utilize the copBL and copAZ gene products to prevent Cu intoxication. We created and examined a ΔcopAZ ΔcopBL mutant strain (cop-). The cop- strain was sensitive to Cu and accumulated intracellular Cu. We screened a transposon (Tn) mutant library in the cop- background and...
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| Publicado no: | Mol Microbiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8121185/ https://ncbi.nlm.nih.gov/pubmed/33034093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14623 |
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