Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life.
Frameshift and nonsense mutations within the gene for human triosephosphate isomerase (TPI) that generate a nonsense codon within the first three-fourths of the protein coding region have been found to reduce the abundance of the product mRNA that copurifies with nuclei. The cellular process and loc...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
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| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
1994
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7969159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.12.8219-8228.1994 |
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