Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life.

Frameshift and nonsense mutations within the gene for human triosephosphate isomerase (TPI) that generate a nonsense codon within the first three-fourths of the protein coding region have been found to reduce the abundance of the product mRNA that copurifies with nuclei. The cellular process and loc...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Belgrader, P, Cheng, J, Zhou, X, Stephenson, L S, Maquat, L E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7969159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.12.8219-8228.1994
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