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Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life.
Frameshift and nonsense mutations within the gene for human triosephosphate isomerase (TPI) that generate a nonsense codon within the first three-fourths of the protein coding region have been found to reduce the abundance of the product mRNA that copurifies with nuclei. The cellular process and loc...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7969159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.12.8219 |
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