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Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease.
To maintain genomic integrity, double-strand breaks (DSBs) in chromosomal DNA must be repaired. In mammalian systems, the analysis of the repair of chromosomal DSBs has been limited by the inability to introduce well-defined DSBs in genomic DNA. In this study, we created specific DSBs in mouse chrom...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359348/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7969147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.12.8096 |
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