Nalaganje...
Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells.
Double-strand breaks (DSBs) are recombinogenic lesions in chromosomal DNA in yeast, Drosophila and Caenorhabditis elegans. Recent studies in mammalian cells utilizing the I-Scel endonuclease have demonstrated that in some immortalized cell lines DSBs in chromosomal DNA are also recombinogenic. We ha...
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| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1995
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307507/ https://ncbi.nlm.nih.gov/pubmed/8559659 |
| Oznake: |
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