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Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease.

To maintain genomic integrity, double-strand breaks (DSBs) in chromosomal DNA must be repaired. In mammalian systems, the analysis of the repair of chromosomal DSBs has been limited by the inability to introduce well-defined DSBs in genomic DNA. In this study, we created specific DSBs in mouse chrom...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Rouet, P, Smih, F, Jasin, M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 1994
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC359348/
https://ncbi.nlm.nih.gov/pubmed/7969147
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