AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: the functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A).

Míreanna Comhchosúla

• Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.
  le: Brewer, G, et al.
  Foilsithe: (1988)
• A cytokine mRNA-destabilizing element that is structurally and functionally distinct from A+U-rich elements
  le: Brown, Cheryl Y., et al.
  Foilsithe: (1996)
• Poly(A) tail shortening is the translation-dependent step in c-myc mRNA degradation.
  le: Laird-Offringa, I A, et al.
  Foilsithe: (1990)
• U-rich sequence-binding proteins (URBPs) interacting with a 20-nucleotide U-rich sequence in the 3' untranslated region of c-fos mRNA may be involved in the first step of c-fos mRNA degradation.
  le: You, Y, et al.
  Foilsithe: (1992)
• Possible relationship of poly(A) shortening to mRNA turnover.
  le: Sheiness, D, et al.
  Foilsithe: (1975)