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Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

The early steps in the degradation of human c-myc mRNA were investigated, using a previously described cell-free mRNA decay system. The first detectable step was poly(A) shortening, which generated a pool of oligoadenylated mRNA molecules. In contrast, the poly(A) of a stable mRNA, gamma globin, was...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Brewer, G, Ross, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1988
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3380094/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.4.1697
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