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Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

The early steps in the degradation of human c-myc mRNA were investigated, using a previously described cell-free mRNA decay system. The first detectable step was poly(A) shortening, which generated a pool of oligoadenylated mRNA molecules. In contrast, the poly(A) of a stable mRNA, gamma globin, was...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Brewer, G, Ross, J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3380094/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.4.1697
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