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A cytokine mRNA-destabilizing element that is structurally and functionally distinct from A+U-rich elements

The control of mRNA stability is crucial to the regulation of cytokine expression. We describe here a novel, potent destabilizing element found in the 3′ untranslated region of granulocyte colony-stimulating factor mRNA. This element, which appears to require at least one stem–loop structure, we ter...

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Main Authors: Brown, Cheryl Y., Lagnado, Cathy A., Goodall, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19403/
https://ncbi.nlm.nih.gov/pubmed/8943001
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