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Possible relationship of poly(A) shortening to mRNA turnover.
Whereas the original size of poly(A) in HeLa cells is about 200 nucleotides, at steady state most of the poly(A) in mRNA contains less than 50 nucleotides. An endonucleolytic attack on poly(A) is suggested as the most likely method to accumulate short pieces of poly(A). Both poly(A) shortening and m...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1975
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1055367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.3.1077 |
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