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The Ribosome as a Hub for Protein Quality Control

Cells face a constant challenge as they produce new proteins. The newly synthesized polypeptides must be folded properly to avoid aggregation. If proteins do misfold, they must be cleared to ensure a functional and healthy proteome. Recent work is revealing the complex mechanisms that work cotransla...

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Bibliografiske detaljer
Main Authors: Pechmann, Sebastian, Willmund, Felix, Frydman, Judith
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593112/
https://ncbi.nlm.nih.gov/pubmed/23395271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.01.020
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