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Interplay between Chaperones and Protein Disorder Promotes the Evolution of Protein Networks
Evolution is driven by mutations, which lead to new protein functions but come at a cost to protein stability. Non-conservative substitutions are of interest in this regard because they may most profoundly affect both function and stability. Accordingly, organisms must balance the benefit of accepti...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4072544/ https://ncbi.nlm.nih.gov/pubmed/24968255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003674 |
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