Organization of the BcgI restriction-modification protein for the cleavage of eight phosphodiester bonds in DNA

Type IIB restriction-modification systems, such as BcgI, feature a single protein with both endonuclease and methyltransferase activities. Type IIB nucleases require two recognition sites and cut both strands on both sides of their unmodified sites. BcgI cuts all eight target phosphodiester bonds be...

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Hlavní autoři: Smith, Rachel M., Marshall, Jacqueline J. T., Jacklin, Alistair J., Retter, Susan E., Halford, Stephen E., Sobott, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592470/
https://ncbi.nlm.nih.gov/pubmed/23147005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1023
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