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Organization of the BcgI restriction–modification protein for the transfer of one methyl group to DNA

The Type IIB restriction–modification protein BcgI contains A and B subunits in a 2:1 ratio: A has the active sites for both endonuclease and methyltransferase functions while B recognizes the DNA. Like almost all Type IIB systems, BcgI needs two unmethylated sites for nuclease activity; it cuts bot...

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Detalhes bibliográficos
Main Authors: Smith, Rachel M., Jacklin, Alistair J., Marshall, Jacqueline J. T., Sobott, Frank, Halford, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592466/
https://ncbi.nlm.nih.gov/pubmed/23147004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1000
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