Substrate DNA and cofactor regulate the activities of a multi-functional restriction-modification enzyme, BcgI.
The BcgI restriction-modification system consists of two subunits, A and B. It is a bifunctional protein complex which can cleave or methylate DNA. The regulation of these competing activities is determined by the DNA substrates and cofactors. BcgI is an active endonuclease and a poor methyltransfer...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1997
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146951/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9278491/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.18.3687 |
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