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Substrate DNA and cofactor regulate the activities of a multi-functional restriction-modification enzyme, BcgI.

The BcgI restriction-modification system consists of two subunits, A and B. It is a bifunctional protein complex which can cleave or methylate DNA. The regulation of these competing activities is determined by the DNA substrates and cofactors. BcgI is an active endonuclease and a poor methyltransfer...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Kong, H, Smith, C L
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146951/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9278491/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.18.3687
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