Substrate DNA and cofactor regulate the activities of a multi-functional restriction-modification enzyme, BcgI.

The BcgI restriction-modification system consists of two subunits, A and B. It is a bifunctional protein complex which can cleave or methylate DNA. The regulation of these competing activities is determined by the DNA substrates and cofactors. BcgI is an active endonuclease and a poor methyltransfer...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Kong, H, Smith, C L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146951/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9278491/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.18.3687
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