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Organization of the BcgI restriction-modification protein for the cleavage of eight phosphodiester bonds in DNA
Type IIB restriction-modification systems, such as BcgI, feature a single protein with both endonuclease and methyltransferase activities. Type IIB nucleases require two recognition sites and cut both strands on both sides of their unmodified sites. BcgI cuts all eight target phosphodiester bonds be...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3592470/ https://ncbi.nlm.nih.gov/pubmed/23147005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1023 |
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