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Caged circular antisense oligonucleotides for photomodulation of RNA digestion and gene expression in cells

We synthesized three 20mer caged circular antisense oligodeoxynucleotides (R20, R20B2 and R20B4) with a photocleavable linker and an amide bond linker between two 10mer oligodeoxynucleotides. With these caged circular antisense oligodeoxynucleotides, RNA-binding affinity and its digestion by ribonuc...

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Detalles Bibliográficos
Autores principales: Wu, Li, Wang, Yuan, Wu, Junzhou, Lv, Cong, Wang, Jie, Tang, Xinjing
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592401/
https://ncbi.nlm.nih.gov/pubmed/23104375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks996
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