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Caged oligonucleotides for bidirectional photomodulation of let-7 miRNA in zebrafish embryos

Many biological functions of microRNA (miRNA) have been identified in the past decade. However, a single miRNA can regulate multiple gene targets, thus it has been a challenge to elucidate the specific functions of each miRNA in different locations and times. New chemical tools make it possible to m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Griepenburg, Julianne C., Ruble, Brittani K., Dmochowski, Ivan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789856/
https://ncbi.nlm.nih.gov/pubmed/23721917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.04.082
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