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Unraveling of a Neutralization Mechanism by Two Human Antibodies against Conserved Epitopes in the Globular Head of H5 Hemagglutinin

The rapid spread of highly pathogenic avian influenza (HPAI) H5N1 virus underscores the importance of effective antiviral treatment. Previously, we developed human monoclonal antibodies 65C6 and 100F4 that neutralize almost all (sub)clades of HPAI H5N1. The conserved 65C6 epitope was mapped to the g...

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主要な著者: Qian, Mengran, Hu, Hongxing, Zuo, Teng, Wang, Guiqin, Zhang, Linqi, Zhou, Paul
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592130/
https://ncbi.nlm.nih.gov/pubmed/23269809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01292-12
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