An Antibody against a Novel and Conserved Epitope in the Hemagglutinin 1 Subunit Neutralizes Numerous H5N1 Influenza Viruses

The spread of the recently emerged, highly pathogenic H5N1 avian influenza virus has raised concern. Preclinical studies suggest that passive immunotherapy could be a new form of treatment for H5N1 virus infection. Here, a neutralizing monoclonal antibody (MAb) against the hemagglutinin (HA) of the...

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Autori principali: Oh, Hsueh-Ling Janice, Åkerström, Sara, Shen, Shuo, Bereczky, Sándor, Karlberg, Helen, Klingström, Jonas, Lal, Sunil K., Mirazimi, Ali, Tan, Yee-Joo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916527/
https://ncbi.nlm.nih.gov/pubmed/20519402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02593-09
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