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Unraveling of a Neutralization Mechanism by Two Human Antibodies against Conserved Epitopes in the Globular Head of H5 Hemagglutinin

The rapid spread of highly pathogenic avian influenza (HPAI) H5N1 virus underscores the importance of effective antiviral treatment. Previously, we developed human monoclonal antibodies 65C6 and 100F4 that neutralize almost all (sub)clades of HPAI H5N1. The conserved 65C6 epitope was mapped to the g...

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Detalhes bibliográficos
Main Authors: Qian, Mengran, Hu, Hongxing, Zuo, Teng, Wang, Guiqin, Zhang, Linqi, Zhou, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592130/
https://ncbi.nlm.nih.gov/pubmed/23269809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01292-12
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