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Unraveling of a Neutralization Mechanism by Two Human Antibodies against Conserved Epitopes in the Globular Head of H5 Hemagglutinin

The rapid spread of highly pathogenic avian influenza (HPAI) H5N1 virus underscores the importance of effective antiviral treatment. Previously, we developed human monoclonal antibodies 65C6 and 100F4 that neutralize almost all (sub)clades of HPAI H5N1. The conserved 65C6 epitope was mapped to the g...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Qian, Mengran, Hu, Hongxing, Zuo, Teng, Wang, Guiqin, Zhang, Linqi, Zhou, Paul
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592130/
https://ncbi.nlm.nih.gov/pubmed/23269809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01292-12
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