Single- and Multiple-Dose Study To Determine the Safety, Tolerability, and Pharmacokinetics of Ceftaroline Fosamil in Combination with Avibactam in Healthy Subjects

This study was conducted to determine the safety, tolerability, and pharmacokinetics of intravenous doses of ceftaroline fosamil administered in combination with the novel non-β-lactam β-lactamase inhibitor avibactam in healthy adults. In the single-dose, open-label arm, 12 subjects received single...

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Main Authors: Riccobene, Todd A., Su, Sheng Fang, Rank, Douglas
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2013
Ábhair:
Clinical Therapeutics
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591900/
https://ncbi.nlm.nih.gov/pubmed/23295928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02134-12
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