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Single- and Multiple-Dose Study To Determine the Safety, Tolerability, and Pharmacokinetics of Ceftaroline Fosamil in Combination with Avibactam in Healthy Subjects

This study was conducted to determine the safety, tolerability, and pharmacokinetics of intravenous doses of ceftaroline fosamil administered in combination with the novel non-β-lactam β-lactamase inhibitor avibactam in healthy adults. In the single-dose, open-label arm, 12 subjects received single...

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Détails bibliographiques
Auteurs principaux: Riccobene, Todd A., Su, Sheng Fang, Rank, Douglas
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591900/
https://ncbi.nlm.nih.gov/pubmed/23295928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02134-12
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