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Single- and Multiple-Dose Study To Determine the Safety, Tolerability, and Pharmacokinetics of Ceftaroline Fosamil in Combination with Avibactam in Healthy Subjects

This study was conducted to determine the safety, tolerability, and pharmacokinetics of intravenous doses of ceftaroline fosamil administered in combination with the novel non-β-lactam β-lactamase inhibitor avibactam in healthy adults. In the single-dose, open-label arm, 12 subjects received single...

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Библиографические подробности
Главные авторы: Riccobene, Todd A., Su, Sheng Fang, Rank, Douglas
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591900/
https://ncbi.nlm.nih.gov/pubmed/23295928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02134-12
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