Preliminary Pharmacokinetic Study of Repeated Doses of Rifampin and Rifapentine in Guinea Pigs

Substitution of rifapentine (RFP) for rifampin (RIF) in the standard antituberculous regimen reduces the time required to cure chronic tuberculosis (TB) infection in mice, but not in guinea pigs. In order to gain insight into these discrepant findings, we conducted a steady-state pharmacokinetic (PK...

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Detaylı Bibliyografya
Asıl Yazarlar: Dutta, Noton K., Alsultan, Abdullah, Peloquin, Charles A., Karakousis, Petros C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591898/
https://ncbi.nlm.nih.gov/pubmed/23295923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01933-12
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